Endocrine Abstracts

Premature ovarian insufficiency (POI) is a disorder in which amenorrhea, associated to elevated levels of gonadotropins, occurs before the age of 40 years.The proband, a 36-year-old woman, was born at term after an uneventful pregnancy and delivery from healthy non-consanguineous parents. Growth and mental developmental milestones were normal. At the age of 12 years she presented menarche followed by regular menses, she had no miscarriage and had a succe...